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| 43 |
theophylline. Twelve subjects were given oral doses of theophylline
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43 |
theophylline. Twelve subjects were given oral doses of theophylline
|
| 44 |
then serum concentrations were measured at 11 time points over the
|
44 |
then serum concentrations were measured at 11 time points over the
|
| 45 |
next 25 hours.
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45 |
next 25 hours.
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| 46 |
|
46 |
|
| 47 |
These data are analyzed in
|
47 |
These data are analyzed in
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| 48 |
\bibcitet{|R:Davidian+Giltinan:1995|Section 5.5\, p.\sspace{}145\, and Section 6.6\, p.\sspace{}176}
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48 |
\bibcitet{|R:Davidian+Giltinan:1995|page 145 in section 5.5 and page
|
| - |
|
49 |
176 in section 6.6}
|
| 49 |
and
|
50 |
and
|
| 50 |
\bibcitet{R:Pinheiro+Bates:2000} using a two-compartment open pharmacokinetic model,
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51 |
\bibcitet{R:Pinheiro+Bates:2000} using a two-compartment open pharmacokinetic model,
|
| 51 |
for which a self-starting model function, \code{SSfol}, is available.
|
52 |
for which a self-starting model function, \code{SSfol}, is available.
|
| 52 |
|
53 |
|
| 53 |
This dataset was originally part of package \CRANpkg{nlme}
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54 |
This dataset was originally part of package \CRANpkg{nlme}
|