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Rev 54591 Rev 81437
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### Kwan, Breault, Umbenhauer, McMahon, and Duggan, (1976) J. of Pharmacokinetics
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### Kwan, Breault, Umbenhauer, McMahon, and Duggan, (1976) J. of Pharmacokinetics
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###  and Biopharmaceutics, 4, 255-280.
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###  and Biopharmaceutics, 4, 255-280.
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### Cited in Davidian and Giltinan (1995), section 2.1
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### Cited in Davidian and Giltinan (1995), section 2.1
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"Indometh" <-
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"Indometh" <-
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  structure(list(
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  structure(list(
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   Subject = structure(ordered(c(1, 1, 1, 1, 1, 1,
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   Subject = ordered(c(1, 1, 1, 1, 1, 1,
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     1, 1, 1, 1, 1, 3, 3, 3, 3, 3, 3, 3, 3, 3, 3, 3, 6, 6, 6, 6, 6,
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     1, 1, 1, 1, 1, 3, 3, 3, 3, 3, 3, 3, 3, 3, 3, 3, 6, 6, 6, 6, 6,
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     6, 6, 6, 6, 6, 6, 2, 2, 2, 2, 2, 2, 2, 2, 2, 2, 2, 4, 4, 4, 4,
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     6, 6, 6, 6, 6, 6, 2, 2, 2, 2, 2, 2, 2, 2, 2, 2, 2, 4, 4, 4, 4,
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     4, 4, 4, 4, 4, 4, 4, 5, 5, 5, 5, 5, 5, 5, 5, 5, 5, 5), levels=1:6),
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     4, 4, 4, 4, 4, 4, 4, 5, 5, 5, 5, 5, 5, 5, 5, 5, 5, 5), levels=1:6,
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     class = c("ordered", "factor"),
 - 
 
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     .Label = c("1", "4", "2", "5", "6", "3")),
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     labels = c("1", "4", "2", "5", "6", "3")),
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   time = c(0.25, 0.5, 0.75, 1, 1.25, 2, 3, 4, 5, 6, 8, 0.25, 0.5,
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   time = c(0.25, 0.5, 0.75, 1, 1.25, 2, 3, 4, 5, 6, 8, 0.25, 0.5,
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     0.75, 1, 1.25, 2, 3, 4, 5, 6, 8, 0.25, 0.5, 0.75, 1, 1.25, 2, 3,
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     0.75, 1, 1.25, 2, 3, 4, 5, 6, 8, 0.25, 0.5, 0.75, 1, 1.25, 2, 3,
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     4, 5, 6, 8, 0.25, 0.5, 0.75, 1, 1.25, 2, 3, 4, 5, 6, 8, 0.25,
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     4, 5, 6, 8, 0.25, 0.5, 0.75, 1, 1.25, 2, 3, 4, 5, 6, 8, 0.25,
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     0.5, 0.75, 1, 1.25, 2, 3, 4, 5, 6, 8, 0.25, 0.5, 0.75, 1, 1.25,
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     0.5, 0.75, 1, 1.25, 2, 3, 4, 5, 6, 8, 0.25, 0.5, 0.75, 1, 1.25,
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     2, 3, 4, 5, 6, 8),
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     2, 3, 4, 5, 6, 8),