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% File nlme/man/PBG.Rd% Part of the nlme package for R% Distributed under GPL 2 or later: see nlme/LICENCE.note\name{PBG}\alias{PBG}\title{Effect of Phenylbiguanide on Blood Pressure}\description{The \code{PBG} data frame has 60 rows and 5 columns.}\format{This data frame contains the following columns:\describe{\item{deltaBP}{a numeric vector}\item{dose}{a numeric vector}\item{Run}{an ordered factor with levels\code{T5} < \code{T4} < \code{T3} < \code{T2} < \code{T1} < \code{P5} < \code{P3} < \code{P2} < \code{P4} < \code{P1}}\item{Treatment}{a factor with levels\code{MDL 72222}\code{Placebo}}\item{Rabbit}{an ordered factor with levels\code{5} < \code{3} < \code{2} < \code{4} < \code{1}}}}\details{Data on an experiment to examine the effect of a antagonist MDL 72222on the change in blood pressure experienced with increasing dosage ofphenylbiguanide are described in Ludbrook (1994) and analyzedin Venables and Ripley (2002, section 10.3). Each of five rabbits was exposed toincreasing doses of phenylbiguanide after having either a placebo orthe HD5-antagonist MDL 72222 administered.}\source{Pinheiro, J. C. and Bates, D. M. (2000), \emph{Mixed-Effects Models in Sand S-PLUS}, Springer, New York. (Appendix A.21)Venables, W. N. and Ripley, B. D. (2002) \emph{Modern AppliedStatistics with S (4th ed)}, Springer, New York.Ludbrook, J. (1994), Repeated measurements and multiple comparisonsin cardiovascular research, \emph{Cardiovascular Research},\bold{28}, 303-311.}%\examples{}\keyword{datasets}