Rev 4851 | Blame | Compare with Previous | Last modification | View Log | Download | RSS feed
\name{Cefamandole}\alias{Cefamandole}\title{Pharmacokinetics of Cefamandole}\description{The \code{Cefamandole} data frame has 84 rows and 3 columns.}\format{This data frame contains the following columns:\describe{\item{Subject}{a factor giving the subject from which the sample was drawn.}\item{Time}{a numeric vector giving the time at which the sample was drawn(minutes post-injection).}\item{conc}{a numeric vector giving the observed plasma concentration ofcefamandole (mcg/ml).}}}\details{Davidian and Giltinan (1995, 1.1, p. 2) describe dataobtained during a pilot study to investigate the pharmacokinetics ofthe drug cefamandole. Plasma concentrations of the drug were measuredon six healthy volunteers at 14 time points following an intraveneousdose of 15 mg/kg body weight of cefamandole.}\source{Pinheiro, J. C. and Bates, D. M. (2000), \emph{Mixed-Effects Models in Sand S-PLUS}, Springer, New York. (Appendix A.4)Davidian, M. and Giltinan, D. M. (1995), \emph{Nonlinear Models forRepeated Measurement Data}, Chapman and Hall, London.}\examples{str(Cefamandole)xyplot(conc ~ Time, Cefamandole, groups = Subject, type = c("g", "b"),aspect = 'xy', scales = list(y = list(log = 2)),auto.key = list(space = "right", lines= TRUE))xyplot(conc ~ Time|Subject, Cefamandole, type = c("g", "b"),index.cond = function(x,y) min(y), aspect = 'xy',scales = list(y = list(log = 2)))#fm1 <- nlsList(SSbiexp, data = Cefamandole)}\keyword{datasets}