\name{Dialyzer} \alias{Dialyzer} \title{High-Flux Hemodialyzer} \description{ The \code{Dialyzer} data frame has 140 rows and 5 columns. } \format{ This data frame contains the following columns: \describe{ \item{Subject}{ a factor with levels \code{A} to \code{T} } \item{QB}{ a factor with levels \code{200} and \code{300} giving the bovine blood flow rate (dL/min). } \item{pressure}{ the transmembrane pressure (dmHg). } \item{rate}{ the hemodialyzer ultrafiltration rate (mL/hr). } \item{index}{ index of observation within subject---1 through 7. } } } \details{ Vonesh and Carter (1992) describe data measured on high-flux hemodialyzers to assess their \emph{in vivo} ultrafiltration characteristics. The ultrafiltration rates (in mL/hr) of 20 high-flux dialyzers were measured at seven different transmembrane pressures (in dmHg). The \emph{in vitro} evaluation of the dialyzers used bovine blood at flow rates of either 200~dl/min or 300~dl/min. The data, are also analyzed in Littell, Milliken, Stroup, and Wolfinger (1996). } \source{ Pinheiro, J. C. and Bates, D. M. (2000), \emph{Mixed-Effects Models in S and S-PLUS}, Springer, New York. (Appendix A.6) Vonesh, E. F. and Carter, R. L. (1992), Mixed-effects nonlinear regression for unbalanced repeated measures, \emph{Biometrics}, \bold{48}, 1-18. Littell, R. C., Milliken, G. A., Stroup, W. W. and Wolfinger, R. D. (1996), \emph{SAS System for Mixed Models}, SAS Institute, Cary, NC. } \examples{ str(Dialyzer) } \keyword{datasets}